What is Hyperthermia? It has been proven that cancer tissues are more vulnerable to heat compared to normal tissues and die at temperatures between 41.6 °C and 44.6 °C. Hyperthermia is a treatment method that uses radio waves to selectively heat and destroy only cancer cells with minimal stress on the body. Its therapeutic effects increase when combined with conventional treatments such as Radiotherapy, Chemotherapy, and Immunotherapy. It also alleviates pain and improves patients' quality of life.

Hyperthermia increases oxygenation in tumor tissue: The most important benefit of increased oxygenation is the enhanced effectiveness of RADIOTHERAPY. Radiotherapy effectiveness can increase by 2-5 times. At the same time, the increased oxygenation also improves the efficacy of some chemotherapy agents.

DNA repair enzymes are inhibited: The main effect of chemotherapy drugs on cancer tissue is to cause DNA damage. When chemotherapy is applied, cells can repair this damage and continue to survive. However, normal cells suffer side effects. Hyperthermia inhibits the enzymes responsible for DNA repair, preventing DNA repair. This makes the applied chemotherapy much more effective. In some tumors, the mechanisms responsible for DNA repair are highly active from the start, causing most treatments to fail. These tumors are considered drug-resistant, but when hyperthermia is applied, they respond to treatment.

Stimulation of the immune system against the tumor: Tumor cells begin to synthesize heat shock proteins to protect themselves from heat-induced protein loss. However, the immune system is programmed to destroy these proteins. While the cancer cell tries to protect itself with these proteins, it is attacked by the body's elite immune cells, the "natural killers". As a result, other subsets of the immune system are activated, and the immune system begins to attack the tumor. This method acts as a natural vaccination induced by heat.

Increased drug uptake due to heating of the cell membrane: Cell membranes are made of fat and are tightly bound to protect the cell. However, as the temperature rises, the membrane softens and becomes more gel-like, loosening its bonds. This allows all substances, especially anticancer drugs, to enter the cell more easily.